{"id":112576,"date":"2025-10-08T19:20:33","date_gmt":"2025-10-09T00:20:33","guid":{"rendered":"https:\/\/milesfortis.com\/?p=112576"},"modified":"2025-10-08T19:20:33","modified_gmt":"2025-10-09T00:20:33","slug":"112576","status":"publish","type":"post","link":"https:\/\/milesfortis.com\/?p=112576","title":{"rendered":""},"content":{"rendered":"<p><a href=\"https:\/\/www.sciencealert.com\/cocoa-extract-supplements-could-reduce-aging-related-chronic-inflammation\">Cocoa Extract Supplements Could Reduce Aging-Related Chronic Inflammation.<\/a><\/p>\n<p>An extract made from cocoa beans may help reduce the risk of cardiovascular disease by reducing age-related inflammation, according to a recent study by an international team of researchers.<\/p>\n<p>The scientists behind the study expanded on <a href=\"https:\/\/doi.org\/10.1093\/ajcn\/nqac055\">previous research<\/a> suggesting that flavanol-rich food and drink, such as chocolate, significantly reduced death by cardiovascular disease.<\/p>\n<p>Found in cocoa beans and other foods such as green tea, apples, and grapes, flavanols have long\u00a0<a href=\"https:\/\/www.sciencealert.com\/a-simple-daily-habit-could-help-lower-your-blood-pressure\">been associated<\/a>\u00a0with a variety of health improvements, including a\u00a0<a href=\"https:\/\/doi.org\/10.3390\/molecules27092901\">role in reducing damage<\/a> caused by excess inflammation.<\/p>\n<p>Inflammation worsens with age in a process commonly referred to as &#8216;<a href=\"https:\/\/www.sciencealert.com\/one-major-feature-of-aging-might-not-be-universal-after-all\">inflammaging<\/a>&#8216;, and is associated with a host of age-related health problems (from\u00a0<a href=\"https:\/\/www.sciencealert.com\/intriguing-study-suggests-inflammation-might-protect-against-not-cause-chronic-back-pain\">chronic pain<\/a>\u00a0to\u00a0<a href=\"https:\/\/www.sciencealert.com\/gut-inflammation-link-to-alzheimers-disease-confirmed-yet-again\">Alzheimer&#8217;s disease<\/a>).<\/p>\n<p>If cocoa supplements can reduce that inflammation, the potential benefits are significant.<\/p>\n<p>&#8220;Our interest in cocoa extract and inflammaging started based on cocoa-related reductions in cardiovascular disease,&#8221;\u00a0<a href=\"https:\/\/www.massgeneralbrigham.org\/en\/about\/newsroom\/press-releases\/cocoa-extract-reduces-inflammation-aging\">says<\/a> Howard Sesso, an epidemiologist from Brigham and Women&#8217;s Hospital in the US.<\/p>\n<p>&#8220;We wanted to see whether multi-year cocoa extract supplementation versus a\u00a0<a class=\"lar_link lar_link_outgoing\" href=\"https:\/\/www.sciencealert.com\/what-is-a-placebo\" target=\"_self\" rel=\"nofollow\" data-linkid=\"102371\" data-postid=\"176435\">placebo<\/a>\u00a0could modulate inflammaging \u2013 and the data suggests it does.&#8221;<\/p>\n<p><!--more--><\/p>\n<figure id=\"attachment_176440\" class=\"wp-caption alignnone\" aria-describedby=\"caption-attachment-176440\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-176440 size-full\" src=\"https:\/\/www.sciencealert.com\/images\/2025\/10\/hsCRPChart-1.jpg\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" srcset=\"https:\/\/www.sciencealert.com\/images\/2025\/10\/hsCRPChart-1.jpg 642w, https:\/\/www.sciencealert.com\/images\/2025\/10\/hsCRPChart-1-418x415.jpg 418w, https:\/\/www.sciencealert.com\/images\/2025\/10\/hsCRPChart-1-600x595.jpg 600w\" alt=\"hsCRP chart\" width=\"642\" height=\"637\" \/><figcaption id=\"caption-attachment-176440\" class=\"wp-caption-text\">hsCRP levels were elevated in blood tests. (Li et al.,\u00a0<em>Age and Ageing<\/em>, 2025)<\/figcaption><\/figure>\n<p>The researchers enlisted 598 healthy adults aged 60 and over who were given either a 500 milligram cocoa extract supplement\u00a0<a href=\"https:\/\/www.sciencealert.com\/what-is-a-placebo\">or a placebo<\/a> each day over two years. Across this period, inflammatory biomarkers in the blood were measured.<\/p>\n<p>Taking the cocoa extract significantly slowed the rise in hsCRP (<a href=\"https:\/\/www.mayoclinic.org\/tests-procedures\/c-reactive-protein-test\/about\/pac-20385228\">high-sensitivity C-reactive protein<\/a>), a general biomarker for systemic inflammation and risk of cardiovascular disease. The greatest effect was detected among those who started the study period with a very high risk of cardiovascular disease.<\/p>\n<p>It&#8217;s not clear what these results mean for overall health. Future research could investigate changes in <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cytokine\">cytokines<\/a>, with signs suggesting a relationship exists between some of these small proteins and the cocoa extract.<\/p>\n<p>&#8220;Interestingly, we also observed an increase in interferon-\u03b3, an immune-related cytokine, which opens new questions for future research,&#8221;\u00a0<a href=\"https:\/\/www.massgeneralbrigham.org\/en\/about\/newsroom\/press-releases\/cocoa-extract-reduces-inflammation-aging\">says<\/a> cardiologist and population geneticist Yanbin Dong, from Augusta University in the US.<\/p>\n<p>&#8220;While cocoa extract is not a replacement for a healthy lifestyle, these results are encouraging and highlight its potential role in modulating inflammation as we age.&#8221;<\/p>\n<p><a href=\"https:\/\/cosmostrial.org\/results\/\">A previous investigation<\/a>\u00a0called the Cocoa Supplement and Multivitamin Outcomes Study found cardiovascular-related deaths were\u00a0<a href=\"https:\/\/doi.org\/10.1093\/ajcn\/nqac055\">27 percent lower<\/a> in a group of seniors taking cocoa supplements.<\/p>\n<p>HsCRP may be driving down that cardiovascular disease risk by reducing inflammation, with research hinting at biological mechanisms that may dial down the background hum of the body&#8217;s immune system.<\/p>\n<p>It&#8217;s noted that the study was in part funded by investigator-initiated grants from Mars Edge, a segment of Mars Incorporated. While this doesn&#8217;t invalidate the findings, confectionery companies could arguably have a vested interest in health-related outcomes of taking cocoa extract.<\/p>\n<p>In the future, such supplements could be taken as a way to manage inflammation and reduce the risk of heart disease, meaning better health for a longer period of time.<\/p>\n<p>&#8220;This study calls for more attention to the advantage of plant-based foods for cardiovascular health, including cocoa products rich in flavanols,&#8221; <a href=\"https:\/\/www.massgeneralbrigham.org\/en\/about\/newsroom\/press-releases\/cocoa-extract-reduces-inflammation-aging\">says<\/a> Sesso.<\/p>\n<p>&#8220;It reinforces the importance of a diverse, colorful, plant-based diet \u2013 especially in the context of inflammation.&#8221;<\/p>\n<p>The research has been published in\u00a0<a href=\"https:\/\/doi.org\/10.1093\/ageing\/afaf269\"><em>Age and Ageing<\/em><\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cocoa Extract Supplements Could Reduce Aging-Related Chronic Inflammation. An extract made from cocoa beans may help reduce the risk of cardiovascular disease by reducing age-related inflammation, according to a recent study by an international team of researchers. The scientists behind the study expanded on previous research suggesting that flavanol-rich food and drink, such as chocolate, &hellip; <a href=\"https:\/\/milesfortis.com\/?p=112576\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-112576","post","type-post","status-publish","format-standard","hentry","category-health-medicine"],"_links":{"self":[{"href":"https:\/\/milesfortis.com\/index.php?rest_route=\/wp\/v2\/posts\/112576","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/milesfortis.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/milesfortis.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/milesfortis.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/milesfortis.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=112576"}],"version-history":[{"count":1,"href":"https:\/\/milesfortis.com\/index.php?rest_route=\/wp\/v2\/posts\/112576\/revisions"}],"predecessor-version":[{"id":112577,"href":"https:\/\/milesfortis.com\/index.php?rest_route=\/wp\/v2\/posts\/112576\/revisions\/112577"}],"wp:attachment":[{"href":"https:\/\/milesfortis.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=112576"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/milesfortis.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=112576"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/milesfortis.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=112576"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}